Saturday, April 6, 2013

Best Buy stores to feature Samsung kiosks

(AP) ? Shares of Best Buy jumped on Thursday after it announced plans to create store-within-store kiosks for Samsung products ? a vote of confidence from a major consumer electronics retailer that the brick-and-mortar format is still an important way to sell products.

Best Buy shares rose more than 16 percent Thurday.

The Minneapolis-based company has battled the "showrooming" effect as more and more people browse in stores and then buy items cheaper online. This has led to fears that the big-box store format is growing obsolete.

But Best Buy has aggressively fought back under new CEO turnaround expert Hubert Joly ? introducing an online price matching policy, giving employees extra training and cutting costs and revamping stores.

The latest deal is a sign that consumer electronics retailers are sticking with the chain. The company will offer Samsung dedicated kiosks at 1,400 Best Buy and Best Buy Mobile stores. Shops will offer the full range of Samsung's mobile products, including smartphones, tablets, laptops, cameras and accessories.

The move shows "a very high-profile consumer electronics vendor still finds Best Buy a relevant distribution outlet," said Morningstar analyst R.J. Hottovy.

It's also a way for Samsung to carve out dedicated retail space without investing in overhead necessary to open its own stores, like its chief rival, Apple Inc., has done.

About 900 Best Buy and Best Buy Mobile stores will be open by early May, with the rest open by early summer.

Janney Capital Markets analyst David Strasser said the deal is an example of Best Buy making merchandising progress. He said it may be a wake-up call that will convince other vendors, like Google, Microsoft and Sony, to invest more with Best Buy.

Best Buy shares rose $3.48 or 16.1 percent, to close at $25.13 Thursday, after briefly reaching a 52-week high of $25.30. The stock has more than doubled since the start of the year.

_____

Online:

www.bestbuy.com/samsungexperienceshop.

.

Associated Press

Source: http://hosted2.ap.org/apdefault/495d344a0d10421e9baa8ee77029cfbd/Article_2013-04-04-US-Best-Buy-Samsung-Kiosks/id-0de8063fa4984ca29eb6eb74646643bf

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Facebook Home + HTC First: Not About Hardware

 Facebook's Futuristic Data Center: Inside Tour

Facebook's Futuristic Data Center: Inside Tour

(click image for larger view and for slideshow) Facebook, together with AT&T and HTC, announced the HTC First at its Menlo Park campus Thursday. The First is notable because it is the first Android smartphone that will ship with Facebook Home, the social network's new home screen software, on board. The HTC First is no Galaxy S 4 or iPhone 5 killer. It is a mid-range smartphone that has middling specs. And that's okay.

The First features a 4.3-inch 1280 x 720p HD display. HTC has shipped a number of devices with this screen size/resolution. While it doesn't quite compare to the full 1080p HD screens of today's best devices, it is far above what many entry-level devices offer. The screen is the one component that is decent -- and there's a good reason for that: Facebook Home wouldn't look all that great on a low-rez screen. In fact, the initial batch of devices that can support Facebook Home have 720p screens or better. A crummy screen would make the Facebook Home experience just as crummy.


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The display is the only hardware feature of the HTC First that matters. Everything else is just an engine to supply the screen with content.

[ Learn more about Facebook Home. Read Facebook Home Wraps Android In Social. ]

Other specs of the device follow the middle of the road. It comes with a Qualcomm Snapdragon 400 processor. The 400 falls below the 600 and 800 series processors, which are Qualcomm's best. The HTC First has just a 5-megapixel camera, though it can shoot 1080p HD video. The user-facing camera rates 1.3 megapixels. The HTC First is compatible with AT&T's LTE 4G network.

The HTC First is not a stunning achievement in hardware design, and it is not meant to be.

The point of this device is to get Facebook Home in front of people at a reasonable price. The First is available for preorder already and reaches AT&T stores April 12. It costs just $99 with a new contract. There's no word on if or when the First will be made available to other carriers.

Facebook wants people to use Facebook Home. Sure, the software is compatible with several existing high-end devices (HTC One, One X, and One X+; Samsung Galaxy Note II, S3, and S4), but it is optional on those devices. Owners of those devices have to *want* to put Facebook Home on their device. Once they see what it does, they may not like it, and may eventually disable it.

It is highly unlikely HTC and Facebook will let First owners disable Facebook Home. They'll be immersed in it from the get-go, and will be living the Facebook dream right out of the box. Facebook is dying for more engagement. It wants as many eyeballs on its software and services as possible. Facebook Home -- and the HTC First -- are a means to an end.

When asked, Facebook CEO Mark Zuckerberg said that the company will not advertise on Facebook Home, at least not right away. He clearly implied that ads are a distinct possibility down the road, though. How does Facebook make money? Ads, at least in part.

The HTC First is a way for Facebook to get a stronger toe-hold on mobile users thanks to Facebook Home.

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Source: http://feeds.informationweek.com/click.phdo?i=dbf58e37435d16ec9b07ace1799c9f63

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Friday, April 5, 2013

Facebook moves to home screens of Android phones

MENLO PARK, Calif. (AP) ? Facebook is unveiling a new experience for Android phones. The idea behind the new Home service is to bring content right to you, on the phone's home screen, rather than require you to check apps on the device.

The event comes amid rapid growth in the number of people who access Facebook from smartphones and tablet computers. More Android integration could help Facebook Inc. attract more mobile advertisers. Though mobile ads were a big concern for Facebook's investors even before the company's initial public offering last May, some of the worry has subsided as the company muscles its way into the market.

Last year, Facebook began showing ads to its mobile audience by shoehorning corporate-sponsored content into users' news feeds, which also include updates from friends and brands they follow. Facebook now faces the challenge of showing people mobile ads without annoying or alienating them.

Facebook's event was being held at its headquarters in Menlo Park, Calif.

Here's a running account of Facebook's event, presented in reverse chronological order. All times are PDT. Presenters include CEO Mark Zuckerberg; Adam Mosseri, director of products; Joey Flynn, product designer. Also appearing were HTC's CEO and AT&T's head of wireless. A question-and-answer session followed the main presentation, which lasted about 45 minutes.

___

11 a.m.

Mosseri says ads will eventually come to this new service. It will be interspersed among the items displayed on the home screen, the way Facebook now injects ads into the main news feed showing friends' photos, links and other posts. But in this case, the ads will take up the entire display.

___

10:55 a.m.

The new Home service won't be available on Apple's iPhone and iPad devices. Apple's iOS and Mac operating systems include features that integrate Facebook's services, but Zuckerberg says doing something like Home would require a closer partnership.

By contrast, Google makes its Android operating system available on an open-source basis, free for anyone to modify, so it's easier to make changes. That said, Facebook makes it clear it's not making a new version of Android, a practice known as forking. Home is being built on top of Android.

___

10:50 a.m.

Minutes after the event ends, Facebook's stock is up 74 cents, or 2.8 percent, at $26.99.

___

10:45 a.m.

Zuckerberg closes the event by expressing his vision of the future, one where people have smartphones and tablet computers rather than desktops and laptops. He says there will be people who have never seen what we call computers these days.

He says Home feeds into that vision.

___

10:40 a.m.

While people will be able to install Home themselves, some phone makers will build Home into the phones. HTC Corp. is releasing a phone called First. It will come in four colors ? red, light blue, white and black. It will run on AT&T Inc.'s 4G LTE cellular network and go on sale April 12 for $100, with advance orders to begin Thursday. A two-year contract requirement is likely.

___

10:35 a.m.

To get Home, simply go to Google's online Play store when it's available. Those with Facebook apps on the phone already will get a prompt to download it. The software will be updated with new features monthly.

It will be available April 12 on certain phones initially.

Facebook isn't making Home for tablet devices for several months, though.

Zuckerberg tells the audience, "We are really proud of Home and we are excited to get (it) into your hands. We think this is the best version of Facebook there is."

___

10:30 a.m.

Flynn unveils a feature called chat heads. The idea is to let you communicate with your friends from that home screen, without needing to open an app. You can chat with multiple people at once that way.

___

10:25 a.m.

Mosseri describes one of the main features of the new service. It's called cover feed.

He notes that when people look at their phones now, they typically see a clock and perhaps the snippet of an email. That will change if you have the Home service activated. As soon as you turn on your phone, you'll see photos. You can swipe from one to the next from the home screen.

___

10:20 a.m.

The new service is called Home. Pictures from your Facebook news feed would take up the entire display screen. Zuckerberg says you'll be seeing the world through people rather than apps.

He gives an example of standing in line at a store and looking down at the phone to see photos of friends and family. It'll be possible to flip through the items. If there's something you like, just double tap on it to "like" it. You can also add comments from the home screen.

With this, Facebook doesn't believe you'll need to go to the Facebook app any more.

___

10:15 a.m.

Zuckerberg says Facebook isn't building a Facebook phone, saying a Facebook-centered device might sell 10 million to 20 million units at best. Rather, it's building on the existing Android system to bring this experience to a wider group of Android users.

___

10:10 a.m.

Zuckerberg talks about a new way to approach Facebook on phones.

He asks, "Why do we need to go into all the apps in the first place to see what is going on with the people we care about?" Better, he says, is to have that experience come right to the home screen, so you're always knowing what is going on around you.

He makes a comparison to the company's news feed feature, which brought friends' posts to a centralized place and reduced the need for people to check their friends' profile pages one by one.

___

10:05 a.m.

Zuckerberg walks on stage and addresses the rumors head on: "Today, we're finally going to talk about that Facebook phone."

He then adds that more specifically, Facebook will talk about turning the Android phone into a simple, social device.

Source: http://news.yahoo.com/facebook-moves-home-screens-android-phones-174821592--finance.html

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Thursday, April 4, 2013

New measurement of crocodilian nerves could help scientists understand ancient animals

Apr. 4, 2013 ? Crocodilians have nerves on their faces that are so sensitive, they can detect a change in a pond when a single drop hits the water surface several feet away. Alligators and crocodiles use these "invisible whiskers" to detect prey when hunting. Now, a new study from the University of Missouri has measured the nerves responsible for this function, which will help biologists understand how today's animals, as well as dinosaurs and crocodiles that lived millions of years ago, interact with the environment around them.

"The trigeminal nerve is the nerve responsible for detection of sensations of the face," said Casey Holliday, assistant professor of anatomy in the MU School of Medicine. "While we've known about these sensitive nerves in crocodiles, we've never measured the size of the nerve bundle, or ganglion, in their skulls, until now. When compared to humans, this trigeminal nerve in crocodiles is huge."

The key to this measurement is a specific hole in the skull. The trigeminal nerve is rooted inside the skull, but must travel through a large hole before it branches out to reach the crocodile's skin on its face. By examining how the skull size, brain size and ganglion size relate to each other, scientists can estimate how sensitive the face is. Eventually, Holliday hopes to measure this nerve in other ancient and contemporary species to learn more about animal behavior.

"Currently, we rely on alligators, crocodiles and birds to provide us with information about how ancient reptiles, such as pre-historic crocodiles and dinosaurs, functioned," said Holliday, who co-authored the study with doctoral student Ian George. "However, the first thing we have to do is to understand how the living animals function."

When comparing the size of the hole for the trigeminal nerve found in alligators to that of certain dinosaurs, George says that the hole in the much-larger dinosaur skull is very similar in size or even smaller, which could give scientists more information about how well dinosaurs could detect small sensations on the face. From there, the scientists can start to trace the evolution of this nerve and the mechanism used by crocodiles.

"Some species of ancient crocodiles lived on land and they probably wouldn't have a use for a sensitive face that can detect disturbances in the water," George said. "So our next step is to trace back and determine when the nerve got bigger and see how that might have paralleled the animals' ecology."

Holliday says that this information will aid future research, including when his team will examine skulls of ancient crocodiles. Understanding this nerve and its functions could also lead to better understanding of the anatomical basis for behavior in many living animals, including fish, electric eels, platypi and humans.

"The same way that we would look at the size of the visual cortex in the brain to understand how well an animal might see, we can now look at the trigeminal nerve in animals to determine how sensitive their skin on their faces is," Holliday said.

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Story Source:

The above story is reprinted from materials provided by University of Missouri-Columbia.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ian D. George, Casey M. Holliday. Trigeminal Nerve Morphology in Alligator mississippiensis and Its Significance for Crocodyliform Facial Sensation and Evolution. The Anatomical Record, 13 FEB 2013 DOI: 10.1002/ar.22666

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/678x3GJOG1g/130404152623.htm

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Leadership Tips: Vol. 413 ? Business Management Daily: Free ...

Sweat it. Robin Chase calls herself a transportation innovator. Co-founder of the Zipcar ride-sharing service, she confirms the famous ratio of inspiration to perspiration. ?The idea was tremendously exciting, but that was just 1% of it,? she says. ?The rest of it was working, slogging, forcing, pushing and fighting to make it happen.?

? Adapted from ?Zipcar: Robin Chase,? Patricia Mertz Esswein, Kiplinger?s Personal Finance.

Imagine it. Robert Lefkowitz, who won the 2012 Nobel Prize in chemistry, had dreamed of practicing medicine. But during a fellowship at the National Institutes of Health ending in 1970, he got hooked on research. He isolated eight common receptors regulating the body?s fight-or-flight response.

? Adapted from Robert J. Lefkowitz, M.D., Howard Hughes Medical Institute.

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? Adapted from ?Say Goodbye to Junk Email,? John Brandon, Inc.

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Autism linked to increased genetic change in regions of genome instability

Apr. 2, 2013 ? Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the chances that a child will develop autism -- a behavioral disorder that affects about 1 of every 88 children in the United States, according to the Centers for Disease Control.

Earlier work had identified, in children with autism, a greater frequency of rare DNA deletions or duplications, known as DNA copy number changes. These rare and harmful events are found in approximately 5 to 10 percent of cases, raising the question as to what other genetic changes might contribute to the disorders known as autism spectrum disorders.

The new research shows that children with autism have -- in addition to these rare events -- an excess of duplicated DNA including more common variants not exclusively found in children with autism, but are found at elevated levels compared to typically developing children.

The research collaboration includes groups led at Penn State by Scott Selleck; at the University of California Davis/MIND Institute by Isaac Pessah, Irva Hertz-Picciotto, Flora Tassone, and Robin Hansen; and at the University of Washington by Evan Eichler.

The investigators also found that the balance of DNA duplications and deletions in children with autism was different from that found in more severe developmental disorders, such as intellectual disability or multiple congenital anomalies, where the levels of both deletions and duplications are increased compared to controls, and are even higher than in children with autism.

They also found that children who had more difficulty with daily living skills also had the greatest level of copy number change throughout their genome. "These measures of adaptive behavior provide an indication of the severity of the impairment in the children with autism. These behaviors were significantly correlated with the amount of DNA copy number change," Selleck said, emphasizing that the research revealed "clear and graded effects of the genetic change."

"These results beg the question as to the origin of this genetic change," Selleck said. "The increased levels of both rare and common variants suggests the possibility that these individuals are predisposed to genetic alteration."

A vigorous debate is ongoing in the research community about the degree of genetic versus environmental contributions to autism. Selleck said the finding of an overall increase in genetic change in children with autism heightens the need to search for the basis of this variation. "We know that environmental factors can affect the stability of the genome, but we don't know if the DNA copy number change we detect in these children is a result of environmental exposures, nutrition, medical factors, lifestyle, genetic susceptibility, or combinations of many elements together," Selleck said. "The elevated levels of common variants is telling us something. It suggests that pure selection of randomly generated variants may not be the whole story."

The Penn State team includes Department of Biochemistry and Molecular Biology Associate Professor Marylyn Ritchie and Assistant Professor Santhosh Girirajan. "The relationship between the level of copy number change and the degree of neurodevelopmental disability is something we have noted previously for large, rare variants" says Girirajan, "but this work extends those observations to common copy number variants, suggesting the level of copy number change in children with autism is larger than we had appreciated." Girirajan, the first author of the study, coordinated the effort between the Penn State and University of Washington researchers.

The research collaboration began with studies supported by the Minnesota Medical Foundation and the Martin Lenz Harrison Endowed Chair in Pediatrics when Selleck was Director of the Autism Initiative at the University of Minnesota. When Selleck arrived at Penn State in 2009, he began a new phase of the analysis with replication studies of early findings conducted with the help and expertise of Evan Eichler and colleagues at the University of Washington using the clinical data and DNA collected by Isaac Pessah, Irva Hertz-Picciotto, Flora Tassone, and Robin Hansen at the University of California Davis/MIND Institute group, which directs a large population-based case-control study of autism called CHARGE (Childhood Autism Risks from Genetics and Environment). In this multiyear study, clinical history, environmental, nutritional, family, and medical data are collected from the families of children with autism and other developmental disorders, as well as from randomly selected control children from the general population. The research took advantage of the CHARGE study, supported by the National Institute of Environmental Health Sciences and the Environmental Protection Agency.

"The CHARGE study is a true population-based case-control cohort for the study of autism, the only one of its kind that I am aware of" says Selleck, and allows for comparisons between the children with autism and controls matched for geographical location and time of birth. The research team plans to continue its collaboration to further characterize the more common genetic variants found to be associated with autism and to explore the relationship between genome variation and environmental exposures.

The research collaboration received financial support from Autism Speaks/Cure Autism Now, the National Institute of Environmental Health Sciences, the Environmental Protection Agency, the University of Minnesota Harrison Autism Initiative Fund, Penn State University, the Minnesota Medical Foundation, the MIND Institute, and the Jane Botsford Johnson Foundation.

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Story Source:

The above story is reprinted from materials provided by Penn State. The original article was written by Scott Selleck / Barbara K. Kennedy.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. S. Girirajan, R. L. Johnson, F. Tassone, J. Balciuniene, N. Katiyar, K. Fox, C. Baker, A. Srikanth, K. H. Yeoh, S. J. Khoo, T. B. Nauth, R. Hansen, M. Ritchie, I. Hertz-Picciotto, E. E. Eichler, I. N. Pessah, S. B. Selleck. Global increases in both common and rare copy number load associated with autism. Human Molecular Genetics, 2013; DOI: 10.1093/hmg/ddt136

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/_cLeSCi0kqc/130403092704.htm

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Wednesday, April 3, 2013

Biological Disciplines Meet To Break, Then Maybe Fix, Bread

60-Second Science

At a conference April 9th to 11th, conservation biologists and synthetic biologists will try to find common ground. Steve Mirsky reports.

More 60-Second Science

Synthetic biologists design and make biological devices and systems for useful purposes. Conservation biologists study biodiversity to protect species and habitat. The two groups don?t talk to each other much. Conservation biologist Kent Redford thus organized a conference, the aim: ?A better communication and an attempt on our part to instill some of our values into the lives and decisions made by synthetic biologists; to change the path that those technologies may take, to make them less environmentally harmful, if not in fact environmentally beneficial.?

The conference, ?How will synthetic biology and conservation shape the future of nature??, is at Clare College in Cambridge, England, April 9th to 11th. Redford, formerly with the Wildlife Conservation Society and now at this own Archipelago Consulting, is a co-author of a paper in the journal PLoS Biology [Kent H. Redford, William Adams, and Georgina M. Mace, Synthetic Biology and Conservation of Nature: Wicked Problems and Wicked Solutions] that frames the issues the conference will begin to address. These include the possibility of resurrecting extinct species, interactions between synthetic and existing organisms, and how the public could be helped or harmed by synthetic biology in, for example, agriculture. ?If we can start that conversation at that meeting, I?ll be a happy guy.?

?Steve Mirsky

[The above text is a transcript of this podcast]

To hear a detailed discussion with Kent Redford, check out the Science Talk podcast, on iTunes or at www.scientificamerican.com


Source: http://rss.sciam.com/click.phdo?i=df2ce9f2bf2e6538b781fd421ae96b8b

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